10.6.1 Number of Profile Files
A system must have access to at least one profile text file. One suggested setup is to have a profile file on each system. However, in a cluster environment it might be more efficient to create a single profile file and store it in a suitable directory on a common, shared disk that all nodes in the cluster have read access to.
Provided that you reference the correct file path (see Section 10.6.3 Calling the Profile File), there is no reason you cannot edit, update, and maintain a profile file in a different location than the suggested default.